Design and performance of a shape-changing accommodating intraocular lens
Posted on 2019-08-13 - 15:08
Presbyopia, the age-related loss of the crystalline lens’ ability to dynamically focus, occurs primarily because of stiffening of lens material, making the ciliary muscle forces insufficient to reshape the lens. Despite its prevalence, there is no satisfactory solution to presbyopia. Here, we present a novel accommodating intraocular lens (A-IOL) able to reshape upon equatorial forces in compliance with the eye’s accommodating mechanism. The concept and design parameters are demonstrated through Finite Element Model simulations and measurements in a manufactured A-IOL prototype, using custom quantitative 3-D OCT (geometrical changes) and Laser Ray Tracing (power changes), with forces radially applied using a custom 8-arm mechanical stretcher. There was an excellent agreement between simulations and measurements (1% for the focal length and 11.4% for geometrical parameters, on average) for radial load of up to 0.6 N. The developed design is expected to achieve ∼2.5 D of effective power change with a polymer material with 0.15-0.25 MPa Young’s Modulus and n=1.44-1.46.
CITE THIS COLLECTION
DataCite
3 Biotech
3D Printing in Medicine
3D Research
3D-Printed Materials and Systems
4OR
AAPG Bulletin
AAPS Open
AAPS PharmSciTech
Abhandlungen aus dem Mathematischen Seminar der Universität Hamburg
ABI Technik (German)
Academic Medicine
Academic Pediatrics
Academic Psychiatry
Academic Questions
Academy of Management Discoveries
Academy of Management Journal
Academy of Management Learning and Education
Academy of Management Perspectives
Academy of Management Proceedings
Academy of Management Review
De La Hoz, Andres; Germann, James; Martinez-Enriquez, Eduardo; Pascual, Daniel; Bekesi, Nandor; Alejandre-Alba, Nicolas; et al. (2019). Design and performance of a shape-changing accommodating intraocular lens. Optica Publishing Group. Collection. https://doi.org/10.6084/m9.figshare.c.4312271
or
Select your citation style and then place your mouse over the citation text to select it.
Resource Link
SHARE
Usage metrics
Read the peer-reviewed publication
AUTHORS (8)
AD
Andres De La Hoz
JG
James Germann
EM
Eduardo Martinez-Enriquez
DP
Daniel Pascual
NB
Nandor Bekesi
NA
Nicolas Alejandre-Alba
CD
Carlos Dorronsoro
SM
Susana Marcos