Digital adaptive optics based on digital lateral shearing of a computed pupil field for point scanning retinal swept source OCT

Posted on 23.02.2021 - 15:16
A novel non-iterative digital adaptive optics technique is presented in which the wavefront error is calculated using the phase difference between the pupil field and its digital copies translated by a pixel along the horizontal and vertical direction in the pupil plane. This method provides slope data per pixel, thus can generate > 50k local slope data samples for a circular pupil of diameter 256 pixels with high sensitivity and dynamic range. It offers more than 12x faster computational speed in comparison to sub-aperture based digital adaptive optics method. Furthermore, it is independent of any system parameters, the light distribution in the pupil plane or the intensity of the image. This technique is implemented in a point scanning swept source OCT at 1060 nm, and a large wavefront error with peak to valley of 20 radians and root mean square error of 0.71 waves is detected and corrected in case of a microbeads phantom sample. Also, human photoreceptor images are recovered from aberrated retinal OCT volumes acquired at eccentricities of 2 and 2.5 degrees from the fovea in-vivo.

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Kumar, Abhishek; Georgiev, Stefan; Salas, Matthias; Leitgeb, Rainer (2021): Digital adaptive optics based on digital lateral shearing of a computed pupil field for point scanning retinal swept source OCT. The Optical Society. Collection. https://doi.org/10.6084/m9.figshare.c.5289307.v1
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AUTHORS (4)

Abhishek Kumar
Stefan Georgiev
Matthias Salas
Rainer Leitgeb
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